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In Today's Issue
- Fact: Poor Sleep Increases The Risk of Death/ Disease
- The News About The Gut Brain Connection
- 1 Quick Technique To Burn More Fat
The News About The Gut Brain Connection
Dear Reader,
It's a fascinating concept... the trillions of tiny microorganisms in our own digestive tract may be sending signals to the brain that influence how we think and behave. Interesting too that close to 70% of our immune cells also reside in our digestive tract and are constantly circulating through the body. Science has moved = from studying pathogenic bacteria (the kind that make us sick) to working to understand more about the beneficial organisms that are naturally part of our body.
The gut/brain connection is a compelling new area of study where experts have come to recognize that the brain and digestive system do indeed talk to each other. Can you manipulate how you feel by managing the bacteria of your digestive tract? The answer is still elusive, but research is working hard to get there.
Landmark studies from Japan over ten years ago had scientists asking a new question about the role bacteria might play in helping animals have the proper stress
response. About five years ago researchers showed that if you were stressed early on in life, you have a lower diversity of gut bacteria when you grow to adulthood, accompanied by behavior changes.
What science has come to understand is that the individual microbiome has an impact on almost every body system. How this communication happens is what remains to be uncovered. There may be multiple mechanisms that the body can use for the digestive system to communicate with the brain.
Bacteria can signal through the vagus nerve, a connector of the enteric nervous system to the central nervous system. Metabolites (small molecules released by bacteria) can be circulated so they interact with the central nervous system.
Continues below...
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The News About The Gut Brain Connection Continued...
Another area that is truly exciting is the research into autism. Parents of these children have been vocal in their belief that there is a very clear connection between the gut and the brain. Researchers including Sarkis Mazmanian, a professor of microbiology at Caltech in California recently published a study that supports autistic parents, finding that the microbiome of autistic kids is different than the best matched, normally developing control subjects. This work has always been
clouded by the fact that autistic kids with GI issues were on restricted (or special) diets. No one knew if it was the autism causes the changes in the microbiome or the diet being followed.
Can such a condition be treated? The team used an organism found in the human digestive system, not something sold as a probiotic, and gave it to the autistic mice. Both the behavior and GI deficits were restored with this approach. Be aware that this has only been found in mice models, so we need to
be careful of leaping too far ahead of the science.
What you need to understand is that while the area gets lots of attention, the research that gives us what we know comes from animal or preclinical studies. There's not a lot of human data out there. Most bacteria won't have a positive or negative effect on the function of your brain. There may be some brining positive effects, but not many. Researchers will need to proceed with caution.
To your good health,
Kirsten Whittaker
Daily Health Bulletin Editor
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Sources:
Original article:
http://www.pri.org/stories/2014-09-08/bacteria-our-gut-may-influence-both-our-physical-and-mental-health
Info on human microbiome:
http://en.wikipedia.org/wiki/Human_microbiome
Study abstract on microbiome and autism, 12.19.13, Cell:
http://www.ncbi.nlm.nih.gov/pubmed/24315484
Sarkis Mazmanian, Caltech:
http://sarkis.caltech.edu/Home.html
More on the gut-microbiome-brain connection:
http://www.nature.com/nrn/journal/v15/n2/full/nrn3669.html
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